Experimental validation studies on a multi-dimensional and multi-scale population balance model of batch granulation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F09%3A00021914" target="_blank" >RIV/60461373:22340/09:00021914 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Experimental validation studies on a multi-dimensional and multi-scale population balance model of batch granulation

Original language description

In this study, a dynamic model is presented for the granulation process, employing a three-dimensional Population balance framework. As a first attempt to account for the multi-scale character of the process, the nucleation and aggregation kernels used in the population balance model are derived using mechanistic representations of the underlying particle physics such as wetting kinetics and energy dissipation effects. Thus, the fundamental properties of the powder and the liquid were used as parametersin the model to predict the granulator dynamics and granule properties. The population balance model is validated against experimental data from a calcite/PVOH-H2O recipe obtained using a lab-scale drum granulator for granule size, fractional binder content and porosity. A reasonably good agreement between experimental and simulation results were obtained for the granule size distribution under different experimental conditions. In addition, accurate model predictions were made for the

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CI - Industrial chemistry and chemical engineering

OECD FORD branch

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Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Chemical Engineering Science

ISSN

0009-2509

e-ISSN

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Volume of the periodical

64

Issue of the periodical within the volume

4

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

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UT code for WoS article

000263773900015

EID of the result in the Scopus database

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