Influence of polyaniline on the potentiometric determination of risedronate with ion-selective membranes

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F10%3A00023389" target="_blank" >RIV/60461373:22340/10:00023389 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Influence of polyaniline on the potentiometric determination of risedronate with ion-selective membranes

Original language description

A novel kind of potentiometric sensor for the determination of risedronate in pharmaceutical products is proposed. This potentiometric sensor is comprised of a poly(vinyl chloride) (PVC) membrane based on an anion-exchanger, tridodecylmethylammonium chloride (TDDMACl), and coated with a polyaniline (PANI) layer. The potentiometric response towards a highly hydrated risedronate species was strongly promoted by the presence of the PANI layer. In contrast to uncoated membranes, the PANI-coated membrane exhibited a sensitivity of ?39.9 ? 0.9 mV decade?1 and the detection limit reached 0.45 mg mL?1. The results of the potentiometric analysis of risedronate agreed with those obtained with a validated chromatographic method. The TDDMACl-based membrane coatedwith the PANI layer differentiated 0.94 wt % and 3.44 wt % of a specific contaminant in 1.6 mg mL?1 risedronate.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Analytical Methods

ISSN

1759-9660

e-ISSN

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Volume of the periodical

2

Issue of the periodical within the volume

10

Country of publishing house

GB - UNITED KINGDOM

Number of pages

4

Pages from-to

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UT code for WoS article

000283959600029

EID of the result in the Scopus database

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