Supramolecular arrangement of guanosine/5''-guanosine monophosphate binary mixtures studied by methods of circular dichroism
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F12%3A43893262" target="_blank" >RIV/60461373:22340/12:43893262 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1002/chir.22045" target="_blank" >http://dx.doi.org/10.1002/chir.22045</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/chir.22045" target="_blank" >10.1002/chir.22045</a>
Alternative languages
Result language
angličtina
Original language name
Supramolecular arrangement of guanosine/5''-guanosine monophosphate binary mixtures studied by methods of circular dichroism
Original language description
Self-assembly of molecules is one of the fundamental processes in biology and in supramolecular chemistry. Guanosine (Guo) and its derivatives are among the widely studied molecules because of self-assembly abilities. Their tetrameric associates are thenature of telomeric DNA, and furthermore they are fundamental building blocks of supramolecular reversible gels, which may arise in certain physical and chemical conditions. Although poorly soluble in water, Guo forms interesting structures with guanosine 5'-monophosphate salt (GMP) in the TRIS buffer. We used electronic circular dichroism and vibrational circular dichroism to describe the thermal response of gels formed by the Guo/GMP binary mixture. Using these complementary techniques suitable to study conformational changes of chiral compounds, we obtained information about the involvement of functional groups and weak interactions in the guanosine quartet (G4) and stacked G4 structures.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Chirality
ISSN
0899-0042
e-ISSN
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Volume of the periodical
24
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
432-438
UT code for WoS article
000303237200012
EID of the result in the Scopus database
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