Hybrid SiO2 stimuli-responsive microparticles

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F12%3A43893674" target="_blank" >RIV/60461373:22340/12:43893674 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Hybrid SiO2 stimuli-responsive microparticles
Original language description
The possibility to control the release of active substances represents one of the most important attributes of targeted drug delivery (TDD). The purpose of this work is to design and characterize microscopic, synthetically created particles from composite material based on silica, thermoresponsive polymer poly-N-isopropylacrylamide (PNIPAM, LCST 32°C) and magnetite nanoparticles, which could be used as a means of such delivery. All of the materials mentioned above provide desired microparticles with unique characteristics such as endurance and hardness of silica, the ability of thermoresponsive polymers to change its volume in dependence on temperature and the possibility of induction heating as a result of the presence of magnetite nanoparticles. By combining these attributes, the final microparticles can act as the vessel for TDD able to transport the delivered substance into its destination an then release it there as a reaction to an external stimulus being the application of alter
Czech name
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Czech description
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Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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