Electrodiffusion Kinetics of Ionic Transport in a Simple Membrane Channel
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F13%3A43895758" target="_blank" >RIV/60461373:22340/13:43895758 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1021/jp407492q" target="_blank" >http://dx.doi.org/10.1021/jp407492q</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/jp407492q" target="_blank" >10.1021/jp407492q</a>
Alternative languages
Result language
angličtina
Original language name
Electrodiffusion Kinetics of Ionic Transport in a Simple Membrane Channel
Original language description
We employ numerical techniques for solving timedependent full Poisson?Nernst?Planck (PNP) equations in 2D to analyze transient behavior of a simple ion channel subject to a sudden electric potential jump across the membrane (voltage clamp). Calculated spatiotemporal profiles of the ionic concentrations and electric potential show that two principal exponential processes can be distinguished in the electrodiffusion kinetics, in agreement with original Planck?s predictions. The initial fast process corresponds to the dielectric relaxation, while the steady state is approached in a second slower exponential process attributed to the nonlinear ionic redistribution. Effects of the model parameters such as the channel length, height of the potential step, boundary concentrations, permittivity of the channel interior, and ionic mobilities on electrodiffusion kinetics are studied. Numerical solutions are used to determine spatiotemporal profiles of the electric field, ionic fluxes, and both th
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CI - Industrial chemistry and chemical engineering
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA203%2F09%2F2091" target="_blank" >GA203/09/2091: Functional dynamics of heterogeneous-chemical and biochemical reaction systems with the use of reaction network analysis</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
JOURNAL OF PHYSICAL CHEMISTRY B
ISSN
1520-6106
e-ISSN
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Volume of the periodical
117
Issue of the periodical within the volume
46
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
1520-6106
UT code for WoS article
000324296400022
EID of the result in the Scopus database
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