Design, Synthesis, Selective Recognition Properties and Targeted Drug Delivery Application
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F14%3A43897833" target="_blank" >RIV/60461373:22340/14:43897833 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1142/9789814417297_0008" target="_blank" >http://dx.doi.org/10.1142/9789814417297_0008</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1142/9789814417297_0008" target="_blank" >10.1142/9789814417297_0008</a>
Alternative languages
Result language
angličtina
Original language name
Design, Synthesis, Selective Recognition Properties and Targeted Drug Delivery Application
Original language description
Porphyrin agents have been studied as photosensitizing anticancer agents and diagnostic probes for many years. The efficiency of their application depends on many factors: intracellular and tissue localization, behaviour in the blood, and specificity forcancer cells. A deep understanding of these characteristics is helpful to prepare better and more effective porphyrin photosensitizers (PSs) and allows design of tailored photodynamic therapy (PDT) for cancer treatment. Porphyrin structure binding and targeted drug delivery properties dramatically influence the above-mentioned characteristics and consequently enhance PDT efficiency; therefore, they can be used to address major applications. Unique biological properties of those compounds are describedin terms of their PDT and molecular recognition properties. In this chapter, methods which can improve porphyrin anticancer efficiency such as targeted transport and combined therapy are listed and discussed. Unique biological properties
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GAP303%2F11%2F1291" target="_blank" >GAP303/11/1291: New types of ligands interfering with cancer cell communication as a new therapeutic strategy</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Handbook of Porphyrin Science
ISBN
978-981-4417-28-0
Number of pages of the result
75
Pages from-to
1-75
Number of pages of the book
488
Publisher name
World Scientific Publishing Company
Place of publication
Singapore
UT code for WoS chapter
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