Inactivation of human pathogenic dermatophytes by non-thermal plasma

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F15%3A43899499" target="_blank" >RIV/60461373:22340/15:43899499 - isvavai.cz</a>

Alternative codes found

RIV/61388971:_____/15:00456143 RIV/00216208:11310/15:10314405 RIV/00216208:11110/15:10314405

Result on the web

<a href="http://www.sciencedirect.com/science/article/pii/S0167701215300737" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0167701215300737</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.mimet.2015.09.017" target="_blank" >10.1016/j.mimet.2015.09.017</a>

Result language

angličtina

Original language name

Inactivation of human pathogenic dermatophytes by non-thermal plasma

Original language description

Non-thermal plasma (NTP) was tested as an in vitro deactivation method on four human pathogenic dermatophytes belonging to all ecological groups including anthropophilic Trichophyton rubrum and Trichophyton interdigitale, zoophilic Arthroderma benhamiae, and geophilic Microsporum gypseum. The identification of all strains was confirmed by sequencing of ITS rDNA region (internal transcribed spacer region of ribosomal DNA). Dermatophyte sporeswere suspended inwater or inoculated on agar plates and exposed to NTP generated by a positive or negative corona discharge, or cometary discharge. After 15 min of exposure to NTP a significant decrease in the number of surviving spores inwater suspensionswas observed in all species. Complete spore inactivation and thus decontamination was observed in anthropophilic species after 25 min of exposure. Similarly, a significant decrease in the number of surviving sporeswas observed after 10-15 min of exposure to NTP on the surface of agar plateswith full inhibition after 25 min in all tested species except ofM. gypseum. Although the sensitivity of dermatophytes to the action of NTP appears to be lower than that of bacteria and yeast, our results suggest that NTP has the potential to be used as an alternative treatment strategy for dermatophytosis and could be useful for surface decontamination in clinical practice.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

BL - Plasma physics and discharge through gases

OECD FORD branch

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Project

<a href="/en/project/ED1.1.00%2F02.0109" target="_blank" >ED1.1.00/02.0109: Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Microbiological Methods

ISSN

0167-7012

e-ISSN

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Volume of the periodical

119

Issue of the periodical within the volume

December

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

53-58

UT code for WoS article

000366442400009

EID of the result in the Scopus database

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