Quantifying the Variability in Resting-State Networks

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F19%3A43918102" target="_blank" >RIV/60461373:22340/19:43918102 - isvavai.cz</a>
Alternative codes found
RIV/67985807:_____/19:00511742 RIV/00023752:_____/19:43920212
Result on the web
<a href="https://www.mdpi.com/1099-4300/21/9/882/htm" target="_blank" >https://www.mdpi.com/1099-4300/21/9/882/htm</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/e21090882" target="_blank" >10.3390/e21090882</a>

Result language
angličtina
Original language name
Quantifying the Variability in Resting-State Networks
Original language description
Recent precision functional mapping of individual human brains has shown that individual brain organization is qualitatively different from group average estimates and that individuals exhibit distinct brain network topologies. How this variability affects the connectivity within individual resting-state networks remains an open question. This is particularly important since certain resting-state networks such as the default mode network (DMN) and the fronto-parietal network (FPN) play an important role in the early detection of neurophysiological diseases like Alzheimer’s, Parkinson’s, and attention deficit hyperactivity disorder. Using different types of similarity measures including conditional mutual information, we show here that the backbone of the functional connectivity and the direct connectivity within both the DMN and the FPN does not vary significantly between healthy individuals for the AAL brain atlas. Weaker connections do vary however, having a particularly pronounced effect on the cross-connections between DMN and FPN. Our findings suggest that the link topology of single resting-state networks is quite robust if a fixed brain atlas is used and the recordings are sufficiently long—even if the whole brain network topology between different individuals is variable.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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