Porphyrin as a versatile visible-light-activatable organic/metal hybrid photoremovable protecting group

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F22%3A43924773" target="_blank" >RIV/60461373:22340/22:43924773 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/22:00126375
Result on the web
<a href="https://www.nature.com/articles/s41467-022-31288-2" target="_blank" >https://www.nature.com/articles/s41467-022-31288-2</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41467-022-31288-2" target="_blank" >10.1038/s41467-022-31288-2</a>

Result language
angličtina
Original language name
Porphyrin as a versatile visible-light-activatable organic/metal hybrid photoremovable protecting group
Original language description
Photoremovable protecting groups (PPGs) represent one of the main contemporary implementations of photochemistry in diverse fields of research and practical applications. For the past half century, organic and metal-complex PPGs were considered mutually exclusive classes, each of which provided unique sets of physical and chemical properties thanks to their distinctive structures. Here, we introduce the meso-methylporphyrin group as a prototype hybrid-class PPG that unites traditionally exclusive elements of organic and metal-complex PPGs within a single structure. We show that the porphyrin scaffold allows extensive modularity by functional separation of the metal-binding chromophore and up to four sites of leaving group release. The insertion of metal ions can be used to tune their spectroscopic, photochemical, and biological properties. We provide a detailed description of the photoreaction mechanism studied by steady-state and transient absorption spectroscopies and quantum-chemical calculations. Our approach applied herein could facilitate access to a hitherto untapped chemical space of potential PPG scaffolds. © 2022, The Author(s).
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10304 - Nuclear physics

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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