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DA_2DCHROM — a data alignment tool for applications on real GC × GC–TOF samples

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F23%3A43925965" target="_blank" >RIV/60461373:22340/23:43925965 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.researchgate.net/publication/369919612_DA_2DCHROM_-_a_data_alignment_tool_for_applications_on_real_GC_GC-TOF_samples#fullTextFileContent" target="_blank" >https://www.researchgate.net/publication/369919612_DA_2DCHROM_-_a_data_alignment_tool_for_applications_on_real_GC_GC-TOF_samples#fullTextFileContent</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s00216-023-04679-7" target="_blank" >10.1007/s00216-023-04679-7</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    DA_2DCHROM — a data alignment tool for applications on real GC × GC–TOF samples

  • Original language description

    Comprehensive two-dimensional gas chromatography coupled with mass spectrometry (GC × GC–MS) has great potential foranalyses of complicated mixtures and sample matrices, due to its separation power and possible high resolution. The secondcomponent of the measurement results, the mass spectra, is reproducible. However, the reproducibility of two-dimensionalchromatography is affected by many factors and makes the evaluation of long-term experiments or cross-laboratory collaborationscomplicated. This paper presents a new open-source data alignment tool to tackle the problem of retention timeshifts — with 5 different algorithms implemented: BiPACE 2D, DISCO, MSort, PAM, and TNT-DA, along with Pearson’scorrelation and dot product as optional methods for mass spectra comparison. The implemented data alignment algorithmsand their variations were tested on real samples to demonstrate the functionality of the presented tool. The suitability of eachimplemented algorithm for significantly/non-significantly shifted data was discussed on the basis of the results obtained.For the evaluation of the “goodness” of the alignment, Kolmogorov–Smirnov test values were calculated, and comparisongraphs were generated. The DA_2DChrom is available online with its documentation, fully open-sourced, and the user canuse the tool without the need of uploading their data to external third-party servers.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10406 - Analytical chemistry

Result continuities

  • Project

    <a href="/en/project/VJ01010123" target="_blank" >VJ01010123: Identification of the perpetrator by forensic analysis of smell and touch traces found at the crime scene</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Analytical and Bioanalytical Chemistry

  • ISSN

    1618-2642

  • e-ISSN

    1618-2650

  • Volume of the periodical

    415

  • Issue of the periodical within the volume

    13

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    11

  • Pages from-to

    "2641–2651"

  • UT code for WoS article

    000967645100002

  • EID of the result in the Scopus database

    2-s2.0-85152464583