Method of production of a composite of yeast-derived beta glucan particle with incorporated poorly-water-soluble low-molecular-weight compound, pharmaceutical preparation and use thereof
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F24%3A43928889" target="_blank" >RIV/60461373:22340/24:43928889 - isvavai.cz</a>
Result on the web
<a href="https://worldwide.espacenet.com/patent/search/family/079554207/publication/EP3946271A1?q=EP3946271" target="_blank" >https://worldwide.espacenet.com/patent/search/family/079554207/publication/EP3946271A1?q=EP3946271</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Method of production of a composite of yeast-derived beta glucan particle with incorporated poorly-water-soluble low-molecular-weight compound, pharmaceutical preparation and use thereof
Original language description
The present invention relates to a formulation of composites cornprised of yeast-derived beta glucan particles (GPs) and water-insoluble or poorly-water-soluble low-rnolecular-weight cornpounds, such as medicaments (drugs) or food supplernents. The composites can exhibit different crystallinity degrees depending on the formulation and, consequently, dissolution kinetics can be controlled. Yeast-derived beta glucan particles are used as carriers for the encapsulation and amorphization of insoluble or poorly-water-soluble low-molecular-weight compounds; amorphous formulations exhibiting faster dissolution rates, and consequently, enhanced oral bioavailability. The present invention further relates to a rnethod of preparation of the composites by spray drying, and the use thereof.
Czech name
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Czech description
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Classification
Type
P - Patent
CEP classification
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OECD FORD branch
20402 - Chemical process engineering
Result continuities
Project
<a href="/en/project/GX19-26127X" target="_blank" >GX19-26127X: The robotic nano-pharmacist: Next-generation manufacturing processes for personalised therapeutic agents</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2024
Confidentiality
U - Předmět řešení projektu je utajovanou skutečností podle zvláštních právních předpisů nebo je skutečností, jejíž zveřejnění by mohlo ohrozit činnost zpravodajské služby. Údaje o projektu jsou upraveny tak, aby byly zveřejnitelné
Data specific for result type
Patent/design ID
EP3946271
Publisher
EPO_1 -
Publisher name
European Patent Office
Place of publication
Munich, The Hague, Berlin, Vienna, Brussels
Publication country
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Date of acceptance
Dec 25, 2024
Owner name
Vysoká škola chemicko-technologická v Praze
Method of use
A - Výsledek využívá pouze poskytovatel
Usage type
A - K využití výsledku jiným subjektem je vždy nutné nabytí licence