Electrochemical Trifluoromethylation of Enamides under Microflow Conditions

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F24%3A43930367" target="_blank" >RIV/60461373:22340/24:43930367 - isvavai.cz</a>
Result on the web
<a href="https://pubs.acs.org/doi/full/10.1021/acs.oprd.4c00311" target="_blank" >https://pubs.acs.org/doi/full/10.1021/acs.oprd.4c00311</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acs.oprd.4c00311" target="_blank" >10.1021/acs.oprd.4c00311</a>

Result language
angličtina
Original language name
Electrochemical Trifluoromethylation of Enamides under Microflow Conditions
Original language description
The development of sustainable trifluoromethylations of enamides is of great interest to the pharmaceutical industry. Herein, we demonstrate a sustainable direct electrochemical trifluoromethylation method in a microflow cell, using Langlois reagent, without the need for a supporting electrolyte, oxidants, or any additive under mild conditions. This method can be applied to various substrates with a yield of up to 84%. Additionally, the batch process yielded significantly less (22%), highlighting the microflow cell's efficiency.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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