Dysnatremia as a poor prognostic indicator in patients with acute subarachnoid hemorrhage

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61383082%3A_____%2F17%3A00000316" target="_blank" >RIV/61383082:_____/17:00000316 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/17:10370438

Result on the web

<a href="https://www.ncbi.nlm.nih.gov/pubmed/26496416" target="_blank" >https://www.ncbi.nlm.nih.gov/pubmed/26496416</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.23736/S0390-5616.16.03411-1" target="_blank" >10.23736/S0390-5616.16.03411-1</a>

Result language

angličtina

Original language name

Dysnatremia as a poor prognostic indicator in patients with acute subarachnoid hemorrhage

Original language description

Dysnatremia occurred in 35.8% patients; this was more frequently hyponatremia (19.8%) with a mean SNa 132.23±2.09 mmol/L, (16.0% mild, 3.2% moderate, 0.6% severe). Hypernatremia occurred less commonly in 11.9%, P<0.001 with a mean SNa 154.21±3.72 mmol/L, (6.1% mild, 2.9% moderate, 2.9% severe). In 4.8% of patients there were episodes of both dysnatremias. The incidence of hypo-osmolar hyponatremia was 6.4%, Cerebral salt wasting (CSW) 3.5%, syndrome of inappropriate secretion of antidiuretic hormone (SIADH) 0.3% and Central diabetes insipidus 1.7%. The hypernatremic patients had a higher inpatient mortality rate (P=0.001) and a worse overall outcome (P<0.001) than those hyponatremic or normotremic patients. Multivariate logistic regression showed that hypernatremia was an independent risk factor for increased inpatient mortality and poor outcome in patients with SAH.Our 10-year targeted sodium management regimen in acute SAH patients showed that dysnatremias were frequent, predominantly hyponatremia of which the more usual causes were CSW and not SIADH. Hypernatremia was shown to be an independent risk factor for inpatient mortality and poor outcome.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

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Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Neurosurgical Sciences

ISSN

0390-5616

e-ISSN

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Volume of the periodical

61

Issue of the periodical within the volume

4

Country of publishing house

IT - ITALY

Number of pages

9

Pages from-to

371-379

UT code for WoS article

000410533100003

EID of the result in the Scopus database

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