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Hydrogen Peroxide Skull Base Specimen Preparation: Singular View of Hidden Topographic Anatomy

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61383082%3A_____%2F21%3A00001061" target="_blank" >RIV/61383082:_____/21:00001061 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11110/21:10435072

  • Result on the web

    <a href="https://pubmed.ncbi.nlm.nih.gov/34542901/" target="_blank" >https://pubmed.ncbi.nlm.nih.gov/34542901/</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.5137/1019-5149.JTN.32790-20.2" target="_blank" >10.5137/1019-5149.JTN.32790-20.2</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Hydrogen Peroxide Skull Base Specimen Preparation: Singular View of Hidden Topographic Anatomy

  • Original language description

    AIM: To present the technical principles of the hydrogen peroxide head preparation method, and to demonstrate the high quality of anatomical studies performed using these specimens, particularly for arachnoid exploration. MATERIAL and METHODS: Five cadaveric heads were set with a 10% formalin solution and then injected with coloured latex. Thereafter, the heads were bleached with hydrogen peroxide solution 20%. Anatomical dissection of all specimens was performed. The skull base was drilled, dura mater gradually resected and outer arachnoid membranes examined and opened. The topographical anatomy was studied. RESULTS: All soft tissues, the brain, cranial nerves, the vasculature, the dura mater and even the arachnoid, were macroscopically intact, which enabled high-quality skull base specimens. In addition, the bone was softened, facilitating the drilling process. The topographical anatomy of anterior clinoid process was selected as an example and depicted in photos. CONCLUSION: High-quality anatomical specimens were obtained using the hydrogen peroxide head preparation. The topographic anatomy was studied from a unique downside-up angle, as well as by following the passage of the key neurovascular structures during its course. We propose the use of this method in neurosurgical training, especially to practice extradural approaches. Moreover this method seems promising as a complementary method for arachnoid studies.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30103 - Neurosciences (including psychophysiology)

Result continuities

  • Project

    <a href="/en/project/NV19-04-00272" target="_blank" >NV19-04-00272: Relationship of meningioma origo to arachnoid membranes, extent of resection and surgical risks</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    TURKISH NEUROSURGERY

  • ISSN

    1019-5149

  • e-ISSN

  • Volume of the periodical

    31

  • Issue of the periodical within the volume

    6

  • Country of publishing house

    TR - TURKEY

  • Number of pages

    5

  • Pages from-to

    962-966

  • UT code for WoS article

    000726794300019

  • EID of the result in the Scopus database