Biomechanical Simulation of Peyronie's Disease

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61383082%3A_____%2F21%3A00001148" target="_blank" >RIV/61383082:_____/21:00001148 - isvavai.cz</a>

Result on the web

<a href="https://pubmed.ncbi.nlm.nih.gov/33790989/" target="_blank" >https://pubmed.ncbi.nlm.nih.gov/33790989/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1155/2021/6669822" target="_blank" >10.1155/2021/6669822</a>

Result language

angličtina

Original language name

Biomechanical Simulation of Peyronie's Disease

Original language description

A pathological disorder of human penile function, known as Peyronie's disease, is characterized by the formation of plaque particles within the tunica albuginea. The plagues in the shape of rigid plate form in the scars as a result of the imperfect healing process. Due to high stiffness, plagues are the source of pain and anomalous deformations during erectile penis function. The authors simulate the biomechanical behavior of the penile structure by a 3D finite element model. The numerical model is based on the real geometrical shape and the tissue structure with consideration of large nonlinear deformations. The penile erection is modeled by the initial strains imposed on the corpus cavernosa. The stress analysis is performed in a case study of various plague locations. The Peyronie's syndrome manifested by the penis angular deviation simulated by the analysis is compared with the clinical data. The computational simulations provide a rational explanation for the clinical observations on patients. The objective is to apply the proposed modeling approach for the development and validation of treatment methods based on the application of shock waves.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30217 - Urology and nephrology

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

APPLIED BIONICS AND BIOMECHANICS

ISSN

1176-2322

e-ISSN

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Volume of the periodical

2021

Issue of the periodical within the volume

Mar

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

1-6

UT code for WoS article

000636271700002

EID of the result in the Scopus database

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