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Impact of narrow band imaging in prediction of histology of advanced colorectal neoplasia

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61383082%3A_____%2F25%3A00001496" target="_blank" >RIV/61383082:_____/25:00001496 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11110/25:10490601 RIV/00216224:14110/25:00144720

  • Result on the web

    <a href="https://pubmed.ncbi.nlm.nih.gov/39789214/" target="_blank" >https://pubmed.ncbi.nlm.nih.gov/39789214/</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1038/s41598-025-85669-w" target="_blank" >10.1038/s41598-025-85669-w</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Impact of narrow band imaging in prediction of histology of advanced colorectal neoplasia

  • Original language description

    We assessed the diagnostic performance of the Narrow-Band Imaging (NBI) International Colorectal Endoscopic Classification (NICE) and the Japan NBI Expert Team classification (JNET) in predicting histological outcomes of advanced colorectal lesions. Additionally, we evaluated the sensitivity and positive predictive value (PPV) of the JNET and NICE classifications individually for high-grade lesions (including HGD adenomas, intramucosal carcinomas, and T1 carcinomas). This was a retrospective analysis of prospectively collected data, involving 211 patients (130 men, mean age 60 years) who underwent colonoscopy with endoscopic resection of advanced colorectal neoplasia (lesions ≥ 10 mm). Lesions were classified using both NICE and JNET criteria, and final histopathological results were used for comparison. Of the 257 lesions analyzed, the NICE classification accurately classifies a large proportion of lesions (93.8%). In JNET classification we observed 77.4% correctly classified lesions. Specifically, the sensitivity and positive predictive value (PPV) of the NICE classification for high-grade lesions were 100% and 24.4%, respectively. For the JNET classification, the sensitivity and PPV for high-grade lesions were 56.6% and 57.7%, respectively. The JNET classification, with a positive predictive value of 57.7% for high-grade colorectal lesions (including HGD adenomas, intramucosal carcinomas, and T1 carcinomas), should be used for decision-making regarding appropriate subsequent endoscopic therapy.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30204 - Oncology

Result continuities

  • Project

    <a href="/en/project/NU22-08-00424" target="_blank" >NU22-08-00424: Development and clinical utility of a new method to identify patients with risk of recurrent colorectal lesions and personalization of their surveillance based on mutation burden and clinical-pathological phenotype</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2025

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    SCIENTIFIC REPORTS

  • ISSN

    2045-2322

  • e-ISSN

  • Volume of the periodical

    15

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    9

  • Pages from-to

    1-9

  • UT code for WoS article

    001395002400034

  • EID of the result in the Scopus database

    2-s2.0-85214868543