The importance of olfactory and trigeminal event-related potentials (OERPs/TERPs) in the assessment of olfactory function in subjects with chronic rhinosinusitis with nasal polyposis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61383082%3A_____%2F25%3A00001553" target="_blank" >RIV/61383082:_____/25:00001553 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/25:10499248 RIV/00216208:11120/25:43928605 RIV/00216208:11130/25:10499248 RIV/00216275:25520/25:39923862 RIV/00064203:_____/25:10499248

Result on the web

<a href="https://pubmed.ncbi.nlm.nih.gov/40583338/" target="_blank" >https://pubmed.ncbi.nlm.nih.gov/40583338/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.32725/jab.2025.006" target="_blank" >10.32725/jab.2025.006</a>

Result language

angličtina

Original language name

The importance of olfactory and trigeminal event-related potentials (OERPs/TERPs) in the assessment of olfactory function in subjects with chronic rhinosinusitis with nasal polyposis

Original language description

Smell impairment (SI) is a well-known symptom of chronic rhinosinusitis with nasal polyps (CRSwNP). The aim of study was to analyze olfactory and trigeminal event-related potentials (OERPs/TERPs) and psychophysical smell tests in subjects with CRSwNP, and its potential role in clinical practice. Methods: Prospective study included 57 subjects. Two investigated groups with CRSwNP and one control group. Group I (n = 20) contained subjects without CRSwNP before septoplasty. Group II (n = 18) contained subjects with CRSwNP without therapy. Group III (n = 19) contained subjects with CRSwNP after intranasal corticosteroid therapy. Sniffin stick identification smell test and OERPs/TERPs were performed in all subjects. Results: According to the psychophysical smell test, SI was detected in 65% of subjects with CRSwNP. In the control Group I (without CRSwNP), the absence of OERPs was 5.0%, whilethe mean absence rate in Groups II, III (with CRSwNP) was 8.1%. The highest percentage of absence of OERPs was registered in Group II (11.1%). Absence of TERPs was detected in an average of 21.6% of CRSwNP subjects. Group III showed the highest percentage of absence of TERPs (32%). In the control Group I, TERPs were absent in 0% of subjects. Conclusion: CRSwNP significantly impairs olfactory function compared to patients without CRSwNP, Absence of TERPs was detected in an average of 21.6% of CRSwNP subjects versus healthy controls (0%). Presence of TERPs appears to be a predictor of preservation of olfactory function

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30206 - Otorhinolaryngology

Project

<a href="/en/project/NU22-09-00493" target="_blank" >NU22-09-00493: Nasal microbiome and molecular immune mechanisms in the prevention and pathogenesis of nasal polyps and chronic rhinitis; relation to olfactory disorders and allergies</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

JOURNAL OF APPLIED BIOMEDICINE

ISSN

1214-021X

e-ISSN

—

Volume of the periodical

23

Issue of the periodical within the volume

2

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

6

Pages from-to

57 - 62

UT code for WoS article

001513490100001

EID of the result in the Scopus database

2-s2.0-105009946465