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A longitudinal study of breath isoprene in healthy volunteers using selected ion flow tube mass spectrometry (SIFT-MS)

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F06%3A00078426" target="_blank" >RIV/61388955:_____/06:00078426 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    A longitudinal study of breath isoprene in healthy volunteers using selected ion flow tube mass spectrometry (SIFT-MS)

  • Original language description

    Thirty volunteers (19 males, 11 females) were recruited for a 6-month study of the volatile compounds in their exhaled breath using the selected ion flow tube mass spectrometry (SIFT-MS) analytical technique. Volunteers provided weekly breath samples between 8:45 am and I pm (before lunch), and the concentrations of several trace compounds were obtained. In this paper, we focus on the isoprene in alveolar breath, which was monitored by SIFT-MS using NO+ precursor ions. The mean isoprene level for all samples was 118 parts per billion (ppb) with a standard deviation of 68 ppb and the range of values for breath samples given is 0-474 ppb. Variability in isoprene levels was similar in most volunteers. Isoprene levels increased immediately after moderate exercise, but returned to normal within 2-3 min for those few volunteers that were investigated. Cholesterol levels analysed for only three of the subjects were not obviously correlated with isoprene concentration in breath.

  • Czech name

    Longitudinální studie izoprénu v dechu zdravých dobrovolníků s použitím hmotnostní spektrometrie v proudové trubici s vybranými ionty

  • Czech description

    Hmotnostní spektrometrie v proudové trubici s vybranými ionty, SIFT-MS byla použita pro monitorování těkavých látek ve vydechovaném vzduchu 30 dobrovolníků (19 mužů, 11 žen) po dobu šesti měsíců. Dobrovolníci poskytli vzorky dechu každý týden mezi 8:45 a13:00 vždy ale před obědem. Tento článek se zaměřuje na měření izoprénu v dechu s použitím prekurzorů NO+. Průměr měřených koncentrací byl 68 miliardtin objemu, a rozsah hodnot byl od neměřitelných hodnot do 474 miliardtin. Izoprén v dechu přímo nekoreluje s věkem pohlavím ani indexem tělěsné hmotnosti.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CF - Physical chemistry and theoretical chemistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Physiological Measurement

  • ISSN

    0967-3334

  • e-ISSN

  • Volume of the periodical

    27

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    10

  • Pages from-to

    13-22

  • UT code for WoS article

  • EID of the result in the Scopus database