Zeolites Promoting Quinoline Synthesis via Friedlander Reaction

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F10%3A00437032" target="_blank" >RIV/61388955:_____/10:00437032 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s11244-010-9603-8" target="_blank" >http://dx.doi.org/10.1007/s11244-010-9603-8</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s11244-010-9603-8" target="_blank" >10.1007/s11244-010-9603-8</a>

Result language
angličtina
Original language name
Zeolites Promoting Quinoline Synthesis via Friedlander Reaction
Original language description
Catalytic performance of zeolites H-BEA, H-MFI, H-FAU and H-MOR, exhibiting textural differences and with different Bronsted and Lewis acid sites concentration, have been studied in the synthesis of quinolines via Friedlander reaction. H-BEA and H-FAU efficiently promoted the condensation of 2-aminoaryl ketones 3 with ethyl acetoacetate (4a) or acetylacetone (4b) under mild reaction conditions, those being the first examples of zeolites as catalysts for this transformation. While H-FAU showed similar catalytic behaviour than that reported for (Al)SBA-15 affording mixtures of quinolines 5 and quinolones 6, H-BEA mainly led to quinolines 5 in almost total selectivity and good yields. However, H-MFI and H-MOR zeolites afforded quinolones 6 as the major reaction product. Methodology reported here was found to be useful for the synthesis of biologically active compounds with excellent yields avoiding unnecessary purifications protocols and tedious work-up procedures.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CF - Physical chemistry and theoretical chemistry
OECD FORD branch
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Project
<a href="/en/project/GD203%2F08%2FH032" target="_blank" >GD203/08/H032: Advanced catalytic processes and materials</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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