Breath Analysis and the Measurement of Total Body Water Using Isotope Dilution - Applications in the Dialysis Clinic
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F13%3A00397720" target="_blank" >RIV/61388955:_____/13:00397720 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.2174/15734110113099990024" target="_blank" >http://dx.doi.org/10.2174/15734110113099990024</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2174/15734110113099990024" target="_blank" >10.2174/15734110113099990024</a>
Alternative languages
Result language
angličtina
Original language name
Breath Analysis and the Measurement of Total Body Water Using Isotope Dilution - Applications in the Dialysis Clinic
Original language description
Determination of fluid status in patients suffering from kidney failure presents particular challenges. In addition to the failure of homeostatic mechanisms controlling fluid status their chronic disease and associated comorbid conditions disturb body composition, for example by causing muscle wasting or obesity. Accurate assessment of fluid status at the bedside would likely inform better clinical decision making. To facilitate this, a near patient method for determining the total body water (TBW) wasdeveloped. Following ingestion of a known amount of D2O, which equilibrates as HDO the TBWD is determined using the dilution principle. Flowing afterglow mass spectrometry accurately measures the concentration of HDO in either breath or the headspace offluids (e.g. dialysate) enabling immediate calculation of TBW without the need for laboratory measurements. A series of clinical studies was undertaken to establish the validity of the method, especially for longitudinal measurements and
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA203%2F00%2F0632" target="_blank" >GA203/00/0632: Chemistry of ions in the gaseous phase and ion-surface collisions</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Current Analytical Chemistry
ISSN
1573-4110
e-ISSN
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Volume of the periodical
9
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
593-599
UT code for WoS article
000324493100009
EID of the result in the Scopus database
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