Interaction of new butyltin citrate complex with lipid model membrane and DNA

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F14%3A00429552" target="_blank" >RIV/61388955:_____/14:00429552 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1007/s10973-014-3805-4" target="_blank" >http://dx.doi.org/10.1007/s10973-014-3805-4</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10973-014-3805-4" target="_blank" >10.1007/s10973-014-3805-4</a>

Result language

angličtina

Original language name

Interaction of new butyltin citrate complex with lipid model membrane and DNA

Original language description

Organotin(IV) complexes show a wide variety of biological activity: bactericidal, fungicidal, caricidal, and pesticidal. Many of them are more effective than traditional heavy metal anticancer drugs. The aim of the present study was to investigate the interaction of a new dibutyltin complex with citric acid (DBTC) with lipid membrane and plasmid DNA. The effect of this compound on the multilamellar liposomes formed with dipalmitoylphosphatidylcholine, dimyristoylphosphatidylcholine, and dimyristoylphosphatidylethanolamine was studied mainly by the means of differential scanning calorimetry and additionally by the steady-state fluorimetry. Calorimetrical results together with fluorescence spectroscopy suggest that investigated complex interacts with lipids and probably locates itself in the hydrophilic part of the membrane. The effect of DBCT on plasmid DNA was investigated using single-molecule florescence technique and time-correlated single photon counting fluorescence correlation sp

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CF - Physical chemistry and theoretical chemistry

OECD FORD branch

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Project

<a href="/en/project/GBP208%2F12%2FG016" target="_blank" >GBP208/12/G016: Controlling structure and function of biomolecules at the molecular scale: theory meets experiment</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Thermal Analysis and Calorimetry

ISSN

1388-6150

e-ISSN

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Volume of the periodical

118

Issue of the periodical within the volume

2

Country of publishing house

HU - HUNGARY

Number of pages

9

Pages from-to

967-975

UT code for WoS article

000344098200047

EID of the result in the Scopus database

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