The study of the oxidation of the natural flavonol fisetin confirmed quercetin oxidation mechanism
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F15%3A00448346" target="_blank" >RIV/61388955:_____/15:00448346 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.electacta.2015.09.144" target="_blank" >http://dx.doi.org/10.1016/j.electacta.2015.09.144</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.electacta.2015.09.144" target="_blank" >10.1016/j.electacta.2015.09.144</a>
Alternative languages
Result language
angličtina
Original language name
The study of the oxidation of the natural flavonol fisetin confirmed quercetin oxidation mechanism
Original language description
Oxidation of the bioactive flavonoid fisetin was studied under inert atmosphere and under ambient conditions. The presence of fast subsequent chemical reactions following the electron transfer was supported by in situ spectroelectrochemistry and identification of products by HPLC-DAD and HPLC?ESI-MS/MS. In the absence of oxygen, 2,6-dihydroxy-2-(3,4-dihydroxybenzoyl)-benzofuran-3(2H)-one was identified as the only oxidation product of fisetin. This product was found also as the main oxidation product inthe presence of oxygen. The oxidation pathway leading to formation of a benzofuranone derivative can be considered as common for flavonols containing C2-C3 double bond, C3-OH group and dihydroxy-substituted phenyl moiety in its structure. This product was not stable and decomposed further even in contact with oxygen coming from eluents during chromatography. Two oxidation pathways occur under ambient conditions. DFT calculations support the result.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CG - Electrochemistry
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Electrochimica acta
ISSN
0013-4686
e-ISSN
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Volume of the periodical
182
Issue of the periodical within the volume
NOV 2015
Country of publishing house
GB - UNITED KINGDOM
Number of pages
6
Pages from-to
544-549
UT code for WoS article
000365075800067
EID of the result in the Scopus database
2-s2.0-84943144066