Serum calcium and phosphorus concentrations and the outcome of calciphylaxis treatment with sodium thiosulfate
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F17%3A00473736" target="_blank" >RIV/61388955:_____/17:00473736 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/17:10361748 RIV/00064165:_____/17:10361748
Result on the web
<a href="http://dx.doi.org/10.1007/s00706-016-1850-3" target="_blank" >http://dx.doi.org/10.1007/s00706-016-1850-3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00706-016-1850-3" target="_blank" >10.1007/s00706-016-1850-3</a>
Alternative languages
Result language
angličtina
Original language name
Serum calcium and phosphorus concentrations and the outcome of calciphylaxis treatment with sodium thiosulfate
Original language description
Calciphylaxis is severe condition with 45-55 % mortality occurring in chronic dialysis patients. Sporadically, the disease may develop in the patients with normal renal function, for example, in the presence of chronic renal inflammation. Sodium thiosulfate (STS) therapy is a treatment modality of calciphylaxis, but mechanism of its action is unknown. We report four cases of calciphylaxis treated with STS, illustrating that its therapeutic effect is not associated with decreased serum calcium or phosphorus concentration. Therapy with intravenous STS was safe and led to subjective improvement, due to pain reduction, and lesions healing in three of four patients. In one patient, complications of diabetes and other co-morbidities led to unfavorable outcome. STS can be considered promising drug in the treatment of calciphylaxis.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10403 - Physical chemistry
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Monatshefte fur Chemie
ISSN
0026-9247
e-ISSN
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Volume of the periodical
148
Issue of the periodical within the volume
3
Country of publishing house
AT - AUSTRIA
Number of pages
6
Pages from-to
435-440
UT code for WoS article
000396528600006
EID of the result in the Scopus database
2-s2.0-84992337625