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Quantification of volatile metabolites in exhaled breath by selected ion flow tube mass spectrometry, SIFT-MS

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F20%3A00531420" target="_blank" >RIV/61388955:_____/20:00531420 - isvavai.cz</a>

  • Result on the web

    <a href="http://hdl.handle.net/11104/0310084" target="_blank" >http://hdl.handle.net/11104/0310084</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.clinms.2020.02.001" target="_blank" >10.1016/j.clinms.2020.02.001</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Quantification of volatile metabolites in exhaled breath by selected ion flow tube mass spectrometry, SIFT-MS

  • Original language description

    Selected ion flow tube mass spectrometry, SIFT-MS, is a non-separative method for direct quantitative analyses of volatile compounds, VOCs, in air and humid breath based on chemical ionization. Selected reagent ions, either H3O+, NO+ or O-2(+) (non-reactive with major components of air), ionize analyte molecules during a defined time in a flow tube by ion-molecule reactions thus producing analyte ions that are characteristic of the neutral analyte VOCs. Concentrations can be calculated in real-time from the ion count rates. Direct on-line analysis of single or multiple breath exhalations or off-line analysis of breath samples collected into bags can be performed. Several volatile breath metabolites have been quantified by SIFT-MS, including ammonia, acetone, hydrogen cyanide, alcohols, pentane, acetic acid, methane, and sulphur compounds. Their potential as biomarkers is discussed. (C) 2020 Published by Elsevier B.V. on behalf of The Association for Mass Spectrometry: Applications to the Clinical Lab (MSACL).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10403 - Physical chemistry

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Clinical mass spectrometry

  • ISSN

    2376-9998

  • e-ISSN

  • Volume of the periodical

    16

  • Issue of the periodical within the volume

    APR 2020

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    7

  • Pages from-to

    18-24

  • UT code for WoS article

    000539276700003

  • EID of the result in the Scopus database

    2-s2.0-85079896166