Electrophoretically Deposited Layers of Octahedral Molybdenum Cluster Complexes: A Promising Coating for Mitigation of Pathogenic Bacterial Biofilms under Blue Light
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F20%3A00535532" target="_blank" >RIV/61388955:_____/20:00535532 - isvavai.cz</a>
Alternative codes found
RIV/61388980:_____/20:00535532 RIV/60461373:22330/20:43921345
Result on the web
<a href="https://pubs.acs.org/doi/10.1021/acsami.0c19036" target="_blank" >https://pubs.acs.org/doi/10.1021/acsami.0c19036</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acsami.0c19036" target="_blank" >10.1021/acsami.0c19036</a>
Alternative languages
Result language
angličtina
Original language name
Electrophoretically Deposited Layers of Octahedral Molybdenum Cluster Complexes: A Promising Coating for Mitigation of Pathogenic Bacterial Biofilms under Blue Light
Original language description
The fight against infective microorganisms is becoming a worldwide priority due to serious concerns about the rising numbers of drug-resistant pathogenic bacteria. In this context, the inactivation of pathogens by singlet oxygen, O2(1Δg), produced by photosensitizers upon light irradiation has become an attractive strategy to combat drug-resistant microbes. To achieve this goal, we electrophoretically deposited O2(1Δg)-photosensitizing octahedral molybdenum cluster complexes on indium-tin oxide-coated glass plates. This procedure led to the first example of molecular photosensitizer layers able to photoinactivate bacterial biofilms. We delineated the morphology, composition, luminescence, and singlet oxygen formation of these layers and correlated these features with their antibacterial activity. Clearly, continuous 460 nm light irradiation imparted the layers with strong antibacterial properties, and the activity of these layers inhibited the biofilm formation and eradicated mature biofilms of Gram-positive Staphylococcus aureus and Enterococcus faecalis, as well as, Gram-negative Pseudomonas aeruginosa and Escherichia coli bacterial strains. Overall, the microstructure-related oxygen diffusivity of the layers and the water stability of the complexes were the most critical parameters for the efficient and durable use. These photoactive layers are attractive for the design of antibacterial surfaces activated by visible light and include additional functionalities such as the conversion of harmful UV/blue light to red light or oxygen sensing.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10403 - Physical chemistry
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
ACS Applied Materials and Interfaces
ISSN
1944-8244
e-ISSN
—
Volume of the periodical
12
Issue of the periodical within the volume
47
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
52492-52499
UT code for WoS article
000595547400022
EID of the result in the Scopus database
2-s2.0-85096535089