Novel screen-printed sensors with chemically deposited boron-doped diamond and their use for voltammetric determination of attention deficit hyperactivity disorder medication atomoxetine

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F22%3A00549362" target="_blank" >RIV/61388955:_____/22:00549362 - isvavai.cz</a>
Alternative codes found
RIV/00216275:25310/22:39919082
Result on the web
<a href="http://hdl.handle.net/11104/0325375" target="_blank" >http://hdl.handle.net/11104/0325375</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.electacta.2021.139642" target="_blank" >10.1016/j.electacta.2021.139642</a>

Result language
angličtina
Original language name
Novel screen-printed sensors with chemically deposited boron-doped diamond and their use for voltammetric determination of attention deficit hyperactivity disorder medication atomoxetine
Original language description
A novel lab-made disposable screen-printed sensor with chemically deposited boron-doped diamond (LM-SP/BDDE) was characterized by scanning electron microscopy (SEM), Raman spectroscopy, and compared to bulk boron-doped diamond electrode (BDDE) and commercially available screen-printed sensor with BDD working electrode (SP/BDDE). The sensors were applied for the determination of atomoxetine (ATX), a pharmaceutically active ingredient used to treat symptoms of attention deficit hyperactivity disorder (ADHD). Using bulk BDDE and a newly developed differential pulse voltammetric (DPV) method with optimized pre-treatment, DPV parameters, and in Britton-Robinson buffer of pH 2, obtained limit of detection (LOD) was 3.7×10−8 mol L−1. Subsequently, this new method was successfully transferred to the tested SP/BDDE sensors and verified on analysis of an ATX-containing drug Strattera 60MG with excellent repeatability (relative standard deviation (RSD) < 2.5% (n = 5)). Moreover, elimination voltammetry with linear scan (EVLS) uncovered multiple (3-5) diffusion-controlled irreversible oxidation steps at all tested sensors.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)

Project
<a href="/en/project/GA20-01589S" target="_blank" >GA20-01589S: New strategies for improving sensing properties of novel electrode materials via their surface pretreatment or modification</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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