Voltammetric study of new psychoactive substance 3-fluorophenmetrazine
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F23%3A00557347" target="_blank" >RIV/61388955:_____/23:00557347 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/23:10478183 RIV/00216208:11110/23:10478183
Result on the web
<a href="http://hdl.handle.net/11104/0331384" target="_blank" >http://hdl.handle.net/11104/0331384</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/elsa.202100223" target="_blank" >10.1002/elsa.202100223</a>
Alternative languages
Result language
angličtina
Original language name
Voltammetric study of new psychoactive substance 3-fluorophenmetrazine
Original language description
Electrochemical oxidation of the new psychoactive substance 3-fluorophenmetrazine (FPM) was studied in phosphate buffers by cyclic voltammetry and differential pulse voltammetry (DPV) on a glassy carbon electrode. The redox potential of FPM in buffered solution strongly depends on pH. Cyclic voltammetry behavior shows the partial influence of adsorption on the electrode process not allowing detailed analysis of the individual steps of the reaction scheme, it means the involvement of electron transfer (E) and chemical reaction (C). Nevertheless, the irreversible shape of the cyclic voltammogram is explained by the participation of hydroxylation nucleophilic addition of water (hydroxylation) after two-electron/two-proton oxidation of molecule at the tetrahydro-1,4-oxazine ring. The suggested mechanism leading to hydroxylated derivative 2-(3-fluorophenyl)-3-methyl-5-hydroxymorfolin is supported by the calculated highest occupied molecular orbital spatial distribution and atomic charges calculations for electrochemically formed radical cation. Infrared spectroelectrochemistry performed during oxidation in acetonitrile/water also supported the formation of this product.nThe analytical method of FPM determination on glassy carbon electrode was developed using DPV with an attained limit of detection = 4.7 μmol/L in phosphate buffer of pH 9. The linear range of the calibration curve is from 7.0 to 107.00 μmol/L, correlation coefficient (r) = 0.9988.n
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Electrochemical Science Advances
ISSN
2698-5977
e-ISSN
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Volume of the periodical
3
Issue of the periodical within the volume
5
Country of publishing house
DE - GERMANY
Number of pages
10
Pages from-to
e2100223
UT code for WoS article
001134957800003
EID of the result in the Scopus database
2-s2.0-85173072555