Application of In situ TR Spectroelectrochemical Techniques in Determination of Redox Mechanism of Bioactive Compounds

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F23%3A00572822" target="_blank" >RIV/61388955:_____/23:00572822 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Application of In situ TR Spectroelectrochemical Techniques in Determination of Redox Mechanism of Bioactive Compounds
Original language description
The electron transfer reactions play an important role in many natural processes. Reactions such as ndissociation, protonation, and reactions with water and other small molecules often occur in nbiotransformation. The reaction schemes involving these chemical reactions coupled to the nelectron transfer can be determined by cyclic voltammetry. Additionally, in nsitu spectroelectrochemistry can efficiently contribute to the determination of oxidation or nreduction mechanism. This technique provides information about the electroactive chromophore during nthe redox process allowing to identification the first reaction intermediates. The final reaction nproducts were identified by chromatographic techniques. This study represents a key role of TR nspectroelectrochemistry in the determination of reaction intermediates in the case of n1,10- phenanthroline derivative substituted by bioactive phenothiazine unit and ndrug 3- fluorophenmetrazine (2-(3-fluorophenyl)-3-methylmorpholine, 3-FPM). Co pound 3-FPMnhave recently appeared as the new psychoactive substance in the drug market.n
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Moderní elektrochemické metody /42./. Sborník přednášek
ISBN
978-80-908947-0-9
ISSN
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e-ISSN
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Number of pages
5
Pages from-to
186-190
Publisher name
Best servis
Place of publication
Ústí nad Labem
Event location
Jetřichovice
Event date
May 22, 2023
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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