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Localizing double and triple bonds in lipid molecules by mass spectrometry

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F24%3A00597826" target="_blank" >RIV/61388955:_____/24:00597826 - isvavai.cz</a>

  • Alternative codes found

    RIV/61388963:_____/24:00597826

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Localizing double and triple bonds in lipid molecules by mass spectrometry

  • Original language description

    This work presents two novel MS-based approaches for localizing double and triple bonds in lipid aliphatic chains. In the first approach, lipids were ionized by atmospheric pressure chemical ionization in the presence of acetonitrile. Collisional activation of the resulting C3H5N adducts yielded structure-informative fragments, enabling the characterization of fatty acids with isolated, cumulated, and conjugated double or triple bonds. The second approach involved forming lithium adducts of ester lipids in an electrospray source. Upon UV photodissociation (UVPD), these ions produced unique fragments via photoinduced cleavages at ester moieties and double bonds.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    10406 - Analytical chemistry

Result continuities

  • Project

    <a href="/en/project/LX22NPO5104" target="_blank" >LX22NPO5104: National Institute for Research of Metabolic and Cardiovascular Diseases</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2024

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů