Electrochemical Surface-Enhanced Raman Spectroscopy of acetaminophen: Adsorption dynamics and charge transfer mechanism

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F25%3A00638249" target="_blank" >RIV/61388955:_____/25:00638249 - isvavai.cz</a>

Alternative codes found

RIV/67985882:_____/25:00638249 RIV/60461373:22340/25:43932037

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S0927775725017042?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0927775725017042?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.colsurfa.2025.137801" target="_blank" >10.1016/j.colsurfa.2025.137801</a>

Result language

angličtina

Original language name

Electrochemical Surface-Enhanced Raman Spectroscopy of acetaminophen: Adsorption dynamics and charge transfer mechanism

Original language description

Electrochemical Surface-Enhanced Raman Spectroscopy (EC-SERS) enables detailed study of molecular adsorption and charge transfer at metal surfaces. This work investigates acetaminophen (AAP) adsorption on a roughened copper electrode using EC-SERS combined with cyclic voltammetry (CV). CV confirms AAP´s electrochemical stability within1000 to 0 mV, allowing analysis of adsorption without redox interference. AAP rapidly adsorbs within eight CV cycles (similar to 13 min), forming stable surface complexes primarily through amine group interactions. Desorption is slower, indicated by gradual changes in electrochemical current and Raman signal during reverse scans. The highest SERS enhancement occurs at600 mV, where optimal charge transfer and molecular orientation maximize signal intensity. Density functional theory calculations support experimental findings, confirming the formation of metal-molecule ´complexes´ consistent with observed vibrational modes. The study highlights the influence of applied potential on adsorption/desorption dynamics and demonstrates copper's promise as an affordable EC-SERS substrate. Despite lower enhancement compared to noble metals, copper's biocompatibility and surface versatility make it suitable for biomedical and environmental sensing applications. These insights contribute to the advancement of electrochemical sensors based on EC-SERS for pharmaceutical and bioanalytical uses.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10403 - Physical chemistry

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Colloids and Surfaces A-Physicochemical and Engineering Aspects

ISSN

0927-7757

e-ISSN

1873-4359

Volume of the periodical

726

Issue of the periodical within the volume

Part 2

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

9

Pages from-to

137801

UT code for WoS article

001542118000005

EID of the result in the Scopus database

2-s2.0-105011479992