Evaluation of nucleoside phosphonates and their analogs and prodrugs for inhibition of orthopoxvirus replication.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F03%3A57030250" target="_blank" >RIV/61388963:_____/03:57030250 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Evaluation of nucleoside phosphonates and their analogs and prodrugs for inhibition of orthopoxvirus replication.

Original language description

We have evaluated a number of analogs and potential oral prodrugs of adefovir, cidofovir and tenofovir for their ability to inhibit the replication of vaccinia virus or cowpox virus in tissue culture cells. A number of these ANP derivatives have activityagainst vaccinia virus and cowpox virus in vitro and should be evaluated for their efficacies in animal models.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CC - Organic chemistry

OECD FORD branch

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Project

<a href="/en/project/IBS4055109" target="_blank" >IBS4055109: Acyclic nucleoside phosponates with antineoplastic activity</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2003

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Antimicrobial Agents and Chemotherapy

ISSN

0066-4804

e-ISSN

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Volume of the periodical

47

Issue of the periodical within the volume

7

Country of publishing house

US - UNITED STATES

Number of pages

6

Pages from-to

2193-2198

UT code for WoS article

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EID of the result in the Scopus database

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