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Homology modeling and SAR analysis of Schistosoma japonicum cathepsin D (SjCD) with statin inhibitors identify a unique active site steric barrier with potential for the design of specific inhibitors

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F05%3A00025458" target="_blank" >RIV/61388963:_____/05:00025458 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Homology modeling and SAR analysis of Schistosoma japonicum cathepsin D (SjCD) with statin inhibitors identify a unique active site steric barrier with potential for the design of specific inhibitors

  • Original language description

    Aspartic protease from Schistosoma japonicum was prepared, and tested with a panel of specific inhibitors.

  • Czech name

    Homologní modelování a analysa SAR analysis katepsinu D Schistosoma japonicum pomocí statinových inhibitorů ukazuje unikátní sterickou bariéru v aktivním místě důležitou pro návrh inhibitorů

  • Czech description

    Byla pripravena aspartatova proteasa ze Schistosoma japonicum a otestována s panelem specifických inhibitorů.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2005

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biological Chemistry

  • ISSN

    1431-6730

  • e-ISSN

  • Volume of the periodical

    386

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    11

  • Pages from-to

    339-349

  • UT code for WoS article

  • EID of the result in the Scopus database