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Antiviral treatment is more effective than smallpox vaccination upon lethal monkeypox virus infection

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F06%3A00053005" target="_blank" >RIV/61388963:_____/06:00053005 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Antiviral treatment is more effective than smallpox vaccination upon lethal monkeypox virus infection

  • Original language description

    This article concerns the comparison of the effectiveness of (1) post-exposure smallpox vaccination and (2) antiviral treatment with either cidofovir (also called HPMC or Vistide) or with a related acyclic nucleoside phosphonate analogue (HPMPO-DAPy) after lethal intratracheal infection of cynomolgus monkeys (Macaca fascicularis) with monkeypoxvirus (MPXV).

  • Czech name

    Protivirová terapie po lethální infekci opičím poxvirem je mnohem efektivnější než vakcinace

  • Czech description

    Ve srovnávací studii bylo ukázáno, že protivirová terapie cidofovirem (HPMPC, Vistide(R)) a obdobným acyklickým nukleosidfosfonátem (HPMPO-DAPy), po lethální intratracheální infekci (Macaca fascicularis) opičím poxvirem (MPXV), je účinnější než vakcinace.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CC - Organic chemistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Nature

  • ISSN

    0028-0836

  • e-ISSN

  • Volume of the periodical

    439

  • Issue of the periodical within the volume

    7077

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    4

  • Pages from-to

    745-748

  • UT code for WoS article

  • EID of the result in the Scopus database