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Lack of interference of common phytoecdysteroids with production of nitric oxide by immune-activated mammalian macrophages

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F08%3A00305720" target="_blank" >RIV/61388963:_____/08:00305720 - isvavai.cz</a>

  • Alternative codes found

    RIV/68378041:_____/08:00305720

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Lack of interference of common phytoecdysteroids with production of nitric oxide by immune-activated mammalian macrophages

  • Original language description

    Effects of selected common phytoecdysteroids on immunobiological responses triggered by lipopolysaccharide and interferon-gamma were tested under in vitro conditions using murine resident peritoneal macrophages. Test compounds represent natural substances isolated from the medicinal plant Leuzea carthamoides. They do not change biosynthesis of nitric oxide.

  • Czech name

    Běžné fytoekdysony neovlivňují produkci oxidu dusnatého u makrofágů savců, aktivovaných imunitními signály

  • Czech description

    Působení vybraných fytoekdysonů na produkci oxidu dusnatého, která byla aktivována lipopolysacharidem a nebo interferonem-gamma bylo testováno v podmínkách in vitro, za použití myších peritonealních makrofagů. Testované látky představují přírodní složkyizolované z léčivé rostliny parchy saflorové (Leuzea carthamoides). Změny v biosyntéze oxidu dusnatého nebyly pozorovány.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CC - Organic chemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA203%2F04%2F0298" target="_blank" >GA203/04/0298: Preparation and structural identification of steroid and non-steroid ligands efficient in interaction with the ecdysteroid receptor</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Steroids

  • ISSN

    0039-128X

  • e-ISSN

  • Volume of the periodical

    73

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    6

  • Pages from-to

    466-471

  • UT code for WoS article

  • EID of the result in the Scopus database