Inhibitor of sarco-endoplasmic reticulum Ca2+-ATPase thapsigargin stimulates production of nitric oxide and secretion of interferon-gamma

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F08%3A00315837" target="_blank" >RIV/61388963:_____/08:00315837 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/08:1539 RIV/68378041:_____/08:00315837
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Inhibitor of sarco-endoplasmic reticulum Ca2+-ATPase thapsigargin stimulates production of nitric oxide and secretion of interferon-gamma
Original language description
Original findings demontrate immunostimulatory properties of thapsigargin, a sesquiterpene lactone of guaianolide type. It activates secretion of interferon gamma and biosynthesis of nitric oxide.
Czech name
Inhibitor Ca2+-ATPasy sarko/endoplasmatického retikula thapsigargin stimuluje produkci oxidu dusnatého a sekreci interferonu-gamma
Czech description
Originální nálezy demonstrují imunostimulační vlastnosti thapsigarginu, seskviterpenového laktonu guainaloidového typu. Thapsigargin aktivuje sekreci interferonu-gamma a biosyntézu oxidu dusnatého.

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Project
<a href="/en/project/GA305%2F07%2F0061" target="_blank" >GA305/07/0061: Immunopharmacological potential of endoplasmic Ca(2+)-ATPase (SERCA) inhibitors</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2008
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Result description