In vitro binding and in vivo biodistribution studies of the neuroprotective peptide humanin using [125I]humanin derivatives

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F09%3A00337442" target="_blank" >RIV/61388963:_____/09:00337442 - isvavai.cz</a>

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

In vitro binding and in vivo biodistribution studies of the neuroprotective peptide humanin using [125I]humanin derivatives

Original language description

Four new, tyrosine containing humanin derivatives were synthesized, the neuroprotective action was evaluated in the T-maze test and the most active ones were radiolabeled with 125I. Under the experimental conditions used, our data do not confirm the existence of specific binding sites for humanin on the neuronal tissue.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

—

Project

<a href="/en/project/ME%20872" target="_blank" >ME 872: Structure-activity study and mechanism of action of analogues of humanin, a novel neuroprotective petide</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Peptides

ISSN

0196-9781

e-ISSN

—

Volume of the periodical

30

Issue of the periodical within the volume

12

Country of publishing house

US - UNITED STATES

Number of pages

9

Pages from-to

—

UT code for WoS article

000272903900043

EID of the result in the Scopus database

—