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Different effect of two synthetic coumarin-stilbene hybrid compounds on phagocyte activity

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F10%3A00356878" target="_blank" >RIV/61388963:_____/10:00356878 - isvavai.cz</a>

  • Alternative codes found

    RIV/68081707:_____/10:00356878 RIV/68081707:_____/10:00391596

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Different effect of two synthetic coumarin-stilbene hybrid compounds on phagocyte activity

  • Original language description

    Synthetic phenylcoumarin derivatives HHC (7-hydroxy-3-(4'-hydroxyphenyl) coumarin) and HHDC (7-hydroxy-3-(4'-hydroxyphenyl)-3,4-dihydrocoumarin) can affect ROS generation in human neutrophils and NO production by RAW 264.7 macrophages. The obtained results highlighted the different effects of HHC and HHDC on fagocyte functions, which might be due to their diverse free radical scavenging properties and lipophilicity features.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    BO - Biophysics

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/MEB0810013" target="_blank" >MEB0810013: Molecular biological perspectives of the pharmacological modulation of the activation of professional phagocytes</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Neuroendocrinology Letters

  • ISSN

    0172-780X

  • e-ISSN

  • Volume of the periodical

    31

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    SE - SWEDEN

  • Number of pages

    6

  • Pages from-to

  • UT code for WoS article

    000288061000014

  • EID of the result in the Scopus database