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The synthesis of piperidine nucleoside analogs-a comparison of several methods to access the introduction of nucleobases

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F11%3A00359135" target="_blank" >RIV/61388963:_____/11:00359135 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.tet.2010.12.029" target="_blank" >http://dx.doi.org/10.1016/j.tet.2010.12.029</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.tet.2010.12.029" target="_blank" >10.1016/j.tet.2010.12.029</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The synthesis of piperidine nucleoside analogs-a comparison of several methods to access the introduction of nucleobases

  • Original language description

    This work deals with the synthesis of piperidine and hydroxypiperidine analogs of nucleosides. Starting from commercially available 3-hydroxypiperidine, proline or 4-hydroxyproline, a series of piperidine derivatives of both purine and pyrimidine nucleobases was prepared. Various methods of nucleobase attachment were evaluated. The prepared compounds were tested for cytostatic, antibacterial, and antiviral properties but no significant activity was found.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CC - Organic chemistry

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Tetrahedron

  • ISSN

    0040-4020

  • e-ISSN

  • Volume of the periodical

    67

  • Issue of the periodical within the volume

    7

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    16

  • Pages from-to

    1485-1500

  • UT code for WoS article

    000287340600013

  • EID of the result in the Scopus database