Characterization of prolactin-releasing peptide: Binding, signaling and hormone secretion in rodent pituitary cell lines endogenously expressing its receptor
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F11%3A00359843" target="_blank" >RIV/61388963:_____/11:00359843 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/11:10105705
Result on the web
<a href="http://dx.doi.org/10.1016/j.peptides.2010.12.011" target="_blank" >http://dx.doi.org/10.1016/j.peptides.2010.12.011</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.peptides.2010.12.011" target="_blank" >10.1016/j.peptides.2010.12.011</a>
Alternative languages
Result language
angličtina
Original language name
Characterization of prolactin-releasing peptide: Binding, signaling and hormone secretion in rodent pituitary cell lines endogenously expressing its receptor
Original language description
The recently discovered prolactin-releasing peptide (PrRP) binds to the PrRP receptor and is involved in endocrine regulation and energy metabolism. However, its main physiological role is currently unknown. Two biologically active isoforms of PrRP exist: the 31 (PrRP31) and the 20 (PrRP20) amino acid forms, which both contain a C-terminal Phe amide sequence. In the present study, the PrRP receptor was immunodetected in three rodent tumor pituitary cell lines: GH3, AtT20 and RC-4B/C cells. Food intake after intracerebroventricular administration of PrRP analogs in fasted mice was followed. Both PrRP31 and PrRP20 decreased food intake, but PrRP13 did not show significant effect.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GAP303%2F10%2F1368" target="_blank" >GAP303/10/1368: New pharmacological interventions influencing energy homeostasis and development of insulin resistance/ type 2 diabetes mellitus</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Peptides
ISSN
0196-9781
e-ISSN
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Volume of the periodical
32
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
811-817
UT code for WoS article
000289707300026
EID of the result in the Scopus database
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