Non-equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F11%3A00366020" target="_blank" >RIV/61388963:_____/11:00366020 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1074/jbc.M111.265249" target="_blank" >http://dx.doi.org/10.1074/jbc.M111.265249</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1074/jbc.M111.265249" target="_blank" >10.1074/jbc.M111.265249</a>
Alternative languages
Result language
angličtina
Original language name
Non-equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface
Original language description
Using selective N-methylation, we systematically investigated the role of peptide bond amide hydrogens at positions B24, B25 and B26 in insulin for the dimerization ability and for the affinity of the hormone towards insulin receptor.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/LC06077" target="_blank" >LC06077: Center of Chemical Genetics</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Biological Chemistry
ISSN
0021-9258
e-ISSN
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Volume of the periodical
286
Issue of the periodical within the volume
42
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
36968-36977
UT code for WoS article
000296538300075
EID of the result in the Scopus database
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