Ligands of estrogen receptors ? and ?, method of their preparation, and pharmaceuticals comprising them
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F12%3A00388664" target="_blank" >RIV/61388963:_____/12:00388664 - isvavai.cz</a>
Alternative codes found
RIV/68378050:_____/12:00388664
Result on the web
<a href="http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8334280.PN.&OS=PN/8334280&RS=PN/8334280" target="_blank" >http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8334280.PN.&OS=PN/8334280&RS=PN/8334280</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Ligands of estrogen receptors ? and ?, method of their preparation, and pharmaceuticals comprising them
Original language description
The invention relates to novel ligands of the estrogen receptors ? and ? of general formula II, which are useful as an active substance of pharmaceuticals, for example pharmaceutical compositions useful for hormone replacement therapy, as well as for thetreatment of tumors and inflammatory diseases. The invention also relates to a novel preparation method of these ligands comprising cyclotrimerization of ethynylestradiol with the appropriate diyne in an organic solvent. Further, the invention relates to pharmaceuticals comprising the novel compounds according to the invention.
Czech name
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Czech description
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Classification
Type
P - Patent
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Patent/design ID
US8334280
Publisher
US001 -
Publisher name
United States Patent and Trademark Office (USPTO)
Place of publication
Alexandria
Publication country
US - UNITED STATES
Date of acceptance
Dec 18, 2012
Owner name
Ústav molekulární genetiky AV ČR, v. v. i. - Ústav organické chemie a biochemie AV ČR, v. v. i. - Přírodovědecká fakulta UK v Praze
Method of use
A - Výsledek využívá pouze poskytovatel
Usage type
N - Využití výsledku jiným subjektem je možné bez nabytí licence (výsledek není licencován)