Evaluation of Anti-Inflammatory Activity of Prenylated Substances Isolated from Morus alba and Morus nigra

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F14%3A00431698" target="_blank" >RIV/61388963:_____/14:00431698 - isvavai.cz</a>
Alternative codes found
RIV/62157124:16370/14:43872745
Result on the web
<a href="http://dx.doi.org/10.1021/np401025f" target="_blank" >http://dx.doi.org/10.1021/np401025f</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/np401025f" target="_blank" >10.1021/np401025f</a>

Result language
angličtina
Original language name
Evaluation of Anti-Inflammatory Activity of Prenylated Substances Isolated from Morus alba and Morus nigra
Original language description
Chromatographic separation of root extracts of Morus alba and M. nigra led to the identification of the 2-arylbenzofurans moracin C (1), mulberrofuran Y (2), and mulberrofuran H (3), and the prenylated flavonoids kuwanon E (4), kuwanon C (5), sanggenon H(6), cudraflavone B (7), and morusinol (8), and the Die Is Alder adducts soroceal (9), and sanggenon E (10). The cytotocity and their antiphlogistic activity, determined as the attenuation of the secretion of TNF-alpha and IL-1 beta and the inhibition of NF-kappa B nuclear translocation in LPS-stimulated macrophages, were evaluated for compounds 1-10.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Project
<a href="/en/project/EE2.3.30.0014" target="_blank" >EE2.3.30.0014: Molecular biology as a tool for integrating biomedical disciplines at VFU Brno</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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