Anionic pregnane compounds, method for their producing and use of them
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F14%3A00435943" target="_blank" >RIV/61388963:_____/14:00435943 - isvavai.cz</a>
Alternative codes found
RIV/67985823:_____/14:00435943
Result on the web
<a href="http://worldwide.espacenet.com/publicationDetails/biblio?CC=EP&NR=2313424B1&KC=B1&FT=D&ND=5&date=20140423&DB=EPODOC&locale=en_EP" target="_blank" >http://worldwide.espacenet.com/publicationDetails/biblio?CC=EP&NR=2313424B1&KC=B1&FT=D&ND=5&date=20140423&DB=EPODOC&locale=en_EP</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Anionic pregnane compounds, method for their producing and use of them
Original language description
This invention relates to pregnane anionic compounds of general formula I in which R1 is ester group, which is able to form ion such as sulfate, pyridinium sulfate, hemisuccinate etc., R2 is hydrogen atom in alpha or beta configuration, and R3 is ester group, as is acetoxy group, nicotinoyloxy group etc., and their pharmaceutically acceptable salts. Compounds of general formula I are preferably produced from the diol of formula II or diol of formula VIII, which are converted according to described sequence of reactions, to compounds of general formula I, in which R1 is ester group, which is able to form ion such as sulfate, pyridinium sulfate, hemisuccinate etc., R2 is hydrogen atom in alpha or beta configuration, and R3 is ester group. The compounds of general formula I are useful as active ingredients for production of pharmaceuticals for the treatment of neurological and psychiatric diseases and conditions associated with excessive activation of NMDA receptors such as neuroprotectiv
Czech name
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Czech description
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Classification
Type
P - Patent
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GAP303%2F12%2F1464" target="_blank" >GAP303/12/1464: Neurosteroid modulation of NMDA receptors</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Patent/design ID
EP2313424
Publisher
EPO_1 -
Publisher name
European Patent Office
Place of publication
Munich, The Hague, Berlin, Vienna, Brussels
Publication country
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Date of acceptance
Apr 23, 2014
Owner name
Ústav organické chemie a biochemie AV ČR, v. v. i. - Fyziologický ústav AV ČR, v. v. i
Method of use
A - Výsledek využívá pouze poskytovatel
Usage type
A - K využití výsledku jiným subjektem je vždy nutné nabytí licence