Through-space transfer of chiral information mediated by a plasmonic nanomaterial

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F15%3A00445924" target="_blank" >RIV/61388963:_____/15:00445924 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1038/NCHEM.2280" target="_blank" >http://dx.doi.org/10.1038/NCHEM.2280</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/NCHEM.2280" target="_blank" >10.1038/NCHEM.2280</a>

Result language

angličtina

Original language name

Through-space transfer of chiral information mediated by a plasmonic nanomaterial

Original language description

The ability to detect chirality gives stereochemically attuned nanosensors the potential to revolutionize the study of biomolecular processes. Such devices may structurally characterize the mechanisms of protein-ligand binding, the intermediates of amyloidogenic diseases and the effects of phosphorylation and glycosylation. We demonstrate that single nanoparticle plasmonic reporters, or nanotags, can enable a stereochemical response to be transmitted from a chiral analyte to an achiral benzotriazole dyemolecule in the vicinity of a plasmon resonance from an achiral metallic nanostructure. The transfer of chirality was verified by the measurement of mirror image surface enhanced resonance Raman optical activity spectra for the two enantiomers of both ribose and tryptophan. Computational modelling confirms these observations and reveals the novel chirality transfer mechanism responsible. This is the first report of colloidal metal nanoparticles in the form of single plasmonic substrates

Czech name

—

Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CF - Physical chemistry and theoretical chemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Nature Chemistry

ISSN

1755-4330

e-ISSN

—

Volume of the periodical

7

Issue of the periodical within the volume

7

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

591-596

UT code for WoS article

000356805300012

EID of the result in the Scopus database

2-s2.0-84932611556