Oxidation of the Flavonolignan Silybin. in situ EPR Evidence of the Spin-Trapped Silybin Radical
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F16%3A00459440" target="_blank" >RIV/61388963:_____/16:00459440 - isvavai.cz</a>
Alternative codes found
RIV/61388971:_____/16:00459440 RIV/61388955:_____/16:00459440 RIV/61989592:15110/16:33161357 RIV/61989592:15310/16:33161357
Result on the web
<a href="http://dx.doi.org/10.1016/j.electacta.2016.04.107" target="_blank" >http://dx.doi.org/10.1016/j.electacta.2016.04.107</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.electacta.2016.04.107" target="_blank" >10.1016/j.electacta.2016.04.107</a>
Alternative languages
Result language
angličtina
Original language name
Oxidation of the Flavonolignan Silybin. in situ EPR Evidence of the Spin-Trapped Silybin Radical
Original language description
Oxidation of natural flavonolignan silybin in an aprotic environment was studied by electrochemical methods, electron paramagnetic resonance (EPR), UV-vis and IR in situ spectroelectrochemistry and chromatographic techniques. The presence of electrochemically generated silybin radical was proven using in situ EPR spectroelectrochemistry by spin trapping method with 5-tert-butoxycarbonyl-5-methyl-1-pyrroline-N-oxide (BMPO) as a spin trap reagent. The adduct of the silybin radical with BMPO was additionally unambiguously identified by UPLC-ESI-MS/MS. For the first time, the flavonolignan radical was detected upon electrochemical oxidation under such conditions. The one-electron oxidation of silybin leads to a hydroxylated silybin derivative. Its specific redox behaviour can reflect its bioefficiency.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CG - Electrochemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Electrochimica acta
ISSN
0013-4686
e-ISSN
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Volume of the periodical
205
Issue of the periodical within the volume
JUL 2016
Country of publishing house
GB - UNITED KINGDOM
Number of pages
6
Pages from-to
118-123
UT code for WoS article
000376138600016
EID of the result in the Scopus database
2-s2.0-84964495041