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Synthesis of Long Oxahelicenes by Polycyclization in a Flow Reactor

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F17%3A00475338" target="_blank" >RIV/61388963:_____/17:00475338 - isvavai.cz</a>

  • Alternative codes found

    RIV/68407700:21230/17:00311607

  • Result on the web

    <a href="http://dx.doi.org/10.1002/anie.201700341" target="_blank" >http://dx.doi.org/10.1002/anie.201700341</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/anie.201700341" target="_blank" >10.1002/anie.201700341</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Synthesis of Long Oxahelicenes by Polycyclization in a Flow Reactor

  • Original language description

    A series of oxahelicenes composed of ortho/meta-annulated benzene/pyridine and 2H-pyran rings were synthesized on the basis of the cobalt(I)-mediated (or rhodium(I)- or nickel(0)-mediated) double, triple, or quadruple [2+2+2] cycloisomerization of branched aromatic hexa-, nona-, or dodecaynes, thus allowing the construction of 6, 9, or 12 rings in a single operation. The use of a flow reactor was found to be beneficial for the multicyclization reactions. The stereogenic centers present in some of the oligoynes steered the helical folding in such a way that the final oxa[9]-, [13]-, [17]- and [19] helicenes were obtained in both enantiomerically and diastereomerically pure form. Specifically, the oxa[19]helicenes beat the current record in the length of a helicene backbone. Single-molecule conductivity was studied by the mechanically controllable break-junction method with a pyridooxa[9]helicene.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10401 - Organic chemistry

Result continuities

  • Project

    <a href="/en/project/GA16-08294S" target="_blank" >GA16-08294S: Giant nonplanar aromatics: The quest for new functional materials</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Angewandte Chemie - International Edition

  • ISSN

    1433-7851

  • e-ISSN

  • Volume of the periodical

    56

  • Issue of the periodical within the volume

    21

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    5

  • Pages from-to

    5839-5843

  • UT code for WoS article

    000400755800033

  • EID of the result in the Scopus database

    2-s2.0-85018612093