New diterpenoid glucoside and flavonoids from Plectranthus scutellarioides (L.) R. Br.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F19%3A00501560" target="_blank" >RIV/61388963:_____/19:00501560 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14740/19:00109325 RIV/62157124:16370/19:43877334
Result on the web
<a href="https://www.sciencedirect.com/science/article/abs/pii/S0254629918308366?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S0254629918308366?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.sajb.2018.08.023" target="_blank" >10.1016/j.sajb.2018.08.023</a>
Alternative languages
Result language
angličtina
Original language name
New diterpenoid glucoside and flavonoids from Plectranthus scutellarioides (L.) R. Br.
Original language description
Three new compounds, diterpenoid glucoside (13S, 15S)-6 beta, 7 alpha, 12 alpha-trihydroxy-13 beta, 16-cyclo-8-abietene11,14- dione 7-O-beta-D-glucoside 1, flavonoids apigenin 7-O-(3''-O-acetyl)-beta-D-glucuronide 2 and apigenin 5-O( 3''-O-acetyl)-beta-D-glucuronide 3, together with known compounds caffeic acid 4, luteolin 5-O-beta-D-glucoside 5 and rosmarinic acid 6 were isolated from the aerial parts of Plectranthus scutellarioides (L.) R. Br. The structures of the new compounds were elucidated by spectroscopic and mass-spectrometric analyses, including 1D-and 2D-NMR. Compound 1 inhibited hyaluronidase by 25% at the concentration of 200 mu M, compounds 2 and 3 showed inhibitory activity on butyrylcholinesterase better than standard galanthamine at the concentration of 100 mu M, and compound 6 is a potent antioxidant with an ORAC value of 2.15 +/- 0.12. (c) 2018 SAAB. Published by Elsevier B. V. All rights reserved.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30104 - Pharmacology and pharmacy
Result continuities
Project
<a href="/en/project/LM2011020" target="_blank" >LM2011020: CEITEC ? open access</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
South African Journal of Botany
ISSN
0254-6299
e-ISSN
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Volume of the periodical
120
Issue of the periodical within the volume
Jan
Country of publishing house
ZA - SOUTH AFRICA
Number of pages
5
Pages from-to
286-290
UT code for WoS article
000456314600038
EID of the result in the Scopus database
2-s2.0-85053839580