Method of detection of analyte active forms and determination of the ability of substances to bind into analyte active sites
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F19%3A00520762" target="_blank" >RIV/61388963:_____/19:00520762 - isvavai.cz</a>
Result on the web
<a href="https://worldwide.espacenet.com/publicationDetails/originalDocument?CC=CA&NR=3006186C&KC=C&FT=D&ND=5&date=20190730&DB=&locale=en_EP#" target="_blank" >https://worldwide.espacenet.com/publicationDetails/originalDocument?CC=CA&NR=3006186C&KC=C&FT=D&ND=5&date=20190730&DB=&locale=en_EP#</a>
DOI - Digital Object Identifier
—
Alternative languages
Result language
angličtina
Original language name
Method of detection of analyte active forms and determination of the ability of substances to bind into analyte active sites
Original language description
Method for detection of active form of analytes in a sample, comprising: - immobilizing analyte(s) on solid carrier surface by adsorption or covalent binding of analyte surface functional groups and carrier functional groups, or via a molecule bound to carrier surface, - incubating immobilized analyte(s) with a detection probe consisting of a compound of molecular weight <= 2500 Da selectively binding to analyte active site, an oligonucleotide tag, and a chemical linker covalently linking the compound and tag, - washing the solid carrier to remove unbound probe, - determining, directly on the solid carrier, the amount of bound detection probe, wherein this amount is proportional to the amount of analyte(s) in the sample. The method has broad application in medicine. Given the sensitivity of only a few dozen molecules, it provides ability to determine protein markers in blood in a concentration yet undetectable.
Czech name
—
Czech description
—
Classification
Type
P - Patent
CEP classification
—
OECD FORD branch
10609 - Biochemical research methods
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Patent/design ID
CA3006186
Publisher
CA001 -
Publisher name
Canadian Intellectual Property Office (CIPO)
Place of publication
Gatineau, Québec
Publication country
CA - CANADA
Date of acceptance
Jul 30, 2019
Owner name
Ústav organické chemie a biochemie AV ČR, v. v. i
Method of use
B - Výsledek je využíván orgány státní nebo veřejné správy
Usage type
A - K využití výsledku jiným subjektem je vždy nutné nabytí licence