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Kinetics of Plasmodium midgut invasion in Anopheles mosquitoes

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F20%3A00532991" target="_blank" >RIV/61388963:_____/20:00532991 - isvavai.cz</a>

  • Result on the web

    <a href="https://doi.org/10.1371/journal.ppat.1008739" target="_blank" >https://doi.org/10.1371/journal.ppat.1008739</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1371/journal.ppat.1008739" target="_blank" >10.1371/journal.ppat.1008739</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Kinetics of Plasmodium midgut invasion in Anopheles mosquitoes

  • Original language description

    Malaria-causing Plasmodium parasites traverse the mosquito midgut cells to establish infection at the basal side of the midgut. This dynamic process is a determinant of mosquito vector competence, yet the kinetics of the parasite migration is not well understood. Here we used transgenic mosquitoes of two Anopheles species and a Plasmodium berghei fluorescence reporter line to track parasite passage through the mosquito tissues at high spatial resolution. We provide new quantitative insight into malaria parasite invasion in African and Indian Anopheles species and propose that the mosquito complement-like system contributes to the species-specific dynamics of Plasmodium invasion.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10608 - Biochemistry and molecular biology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    PLoS Pathogens

  • ISSN

    1553-7366

  • e-ISSN

  • Volume of the periodical

    16

  • Issue of the periodical within the volume

    9

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    19

  • Pages from-to

    e1008739

  • UT code for WoS article

    000573820300005

  • EID of the result in the Scopus database

    2-s2.0-85092259087