Chiral recognition via a stereodynamic vanadium probe using the electronic circular dichroism effect in differential Raman scattering

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F21%3A00547255" target="_blank" >RIV/61388963:_____/21:00547255 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1039/D1CP03020E" target="_blank" >https://doi.org/10.1039/D1CP03020E</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/d1cp03020e" target="_blank" >10.1039/d1cp03020e</a>

Result language
angličtina
Original language name
Chiral recognition via a stereodynamic vanadium probe using the electronic circular dichroism effect in differential Raman scattering
Original language description
Intermolecular interactions sensitive to chirality occur in many biological events. We report a complex formation between a versatile vanadium-based probe and a chiral co-ligand monitored via the combination of electronic circular dichroism (ECD) and Raman scattering. This “ECD-Raman” effect was discovered relatively recently and can be measured using a Raman optical activity (ROA) spectrometer. Simulated spectra based on experimental ECD and degree of circularity (DOC) values agree with the observed ones. Sensitive recognition of the chiral enantiopure co-ligand is thus enabled by a combination of resonance of the excitation light with the diastereoisomeric complex, co-ligand complexation, circular dichroism, and polarized Raman scattering from the achiral solvent. Relatively dilute solutions could be detected (10−4 mol dm−3), about 1000× less than is necessary for conventional ROA detection of the pure co-ligand and comparable to concentrations needed for conventional ECD spectroscopy. The results thus show that differential ECD-Raman measurements can be conveniently used to monitor molecular interactions and molecular spectroscopic properties.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10403 - Physical chemistry

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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